The legality and side effects of Theophylline
You should always consider the risks of a nootropic before you use it.
Supplements and drugs can interact with Theophylline to increase or decrease the positive or negative effects you experience. If you are already using any supplements or drugs, speak with your trusted medical professional before you experiment with Theophylline. To learn more about the potential interactions between Theophylline and other substances, use interaction-checker.
Is your country not included? Learn how to find out if Theophylline is legal in your country.
The contents herein are not legal advice or a substitute for legal counsel. information is not intended to create, and receipt of it does not constitute, an attorney-client relationship. While we have done our best to be as accurate as possible in the information we convey to you about the legality of nootropics, there is a risk for inaccuracies and errors. If you’re uncertain about the legality of any of your actions, contact a legal counsel or your local authorities governing the legality of various substances you may want to use/import/travel with.
Studies conducted on the effects of Theophylline in healthy humans
No placebo-controlled trials on healthy humans that meet our inclusion criteria have been conducted on Theophylline.
"Subjective ratings showed that subjects were significantly more alert with theophylline than with enprofylline. Subjects reported themselves as significantly more dizzy and ill with both active drugs compared with placebo."
It should be noted that large doses (300-400mg) of Theophylline was used in this study, which may be the reason for the adverse effects seen after 4 weeks of use. "Single doses of theophylline did not significantly alter mood, but marked adverse effects were encountered in the repeated dose phase, possibly related to unpleasant side-effects. Both EEG and EMG findings indicative of stimulation were associated with a single dose of theophylline, but substantial tolerance developed during 4 weeks of therapy."
"Caffeine and theophylline increase psychomotor performance measures of attention at low plasma concentrations in healthy elderly volunteers. This effect is not increased by higher drug concentrations and there is trend towards a return to placebo scores. The lack of effect of both caffeine and theophylline on subjective measures is consistent with previous studies of caffeine in the elderly."
"low doses of oral theophylline result in a significant disturbance in sleep quality in normal nonasthmatic subjects..."
"In the daytime administration, daytime mean sleep latency was increased by both doses and performance was improved by the high dose but not the low dose. In the nighttime administration, nocturnal sleep onset was delayed and total wake time was increased by the high dose but not the low dose. The low dose increased the amount of light stage 1 sleep without producing wakefulness."
"... theophylline does not affect sleep quality or cognitive performance in normal adults.."
Last updated Saturday, June 10, 2023