Theacrine is a stimulating compound found naturally in the leaves of several plants. People report it improves their focus, mood, and energy. But is it effective? Read on to find out what the science says.
This nootropic has no healthy human placebo-controlled studies that meet our inclusion criteria. Negative side effects can occur if used carelessly, so make sure you’re aware of the risks of Theacrine.
Read about the effects of Theacrine in relation to the amount of evidence we've found
Why do people use theacrine?
People who self-experiment with theacrine often state they use it to improve their:
There is a lack of solid scientific evidence for the effectiveness of theacrine for any of these purposes, especially in healthy humans. Preliminary evidence suggests theacrine might be effective for these purposes.
Can theacrine increase energy levels?
In the one study that exists which studied theacrine when not combined with other substances, participants were given 200mg or 400mg theacrine and then they were administered Visual Analogue Scales that enabled researchers to measure the subjective cognitive and affective state of the participants:
"Energy, focus, and concentration increased from baseline values in both doses [...] VAS responses in the 200 mg for willingness to exercise, anxiety, motivation to train and libido increased across the measurement period while no such change was seen with the 400 mg dose." 
It should be noted that there were only 15 participants in this study. Each participant received each dose (including placebo) at separate sessions of cognitive performance and mood testing. This study design is called a placebo-controlled cross-over design.
The legality and side effects of Theacrine
Frequently asked questions about Theacrine
Studies conducted on the effects of Theacrine in healthy humans
Last updated Saturday, June 10, 2023