Other names Pramiracetam Sulfate, CI-879


Pramiracetam is considered by many as a stimulating memory enhancer useful for studying. But how science-backed is it really? Read on to find out.

This nootropic has no healthy human placebo-controlled studies that meet our inclusion criteria. Negative side effects can occur if used carelessly, so make sure you’re aware of the risks of Pramiracetam.


Read about the effects of Pramiracetam in relation to the amount of evidence we've found

Why do people use pramiracetam?

People who self-experiment with pramiracetam often state they use it to improve their:

  • Memory
  • Focus
  • Learning
  • Energy
There is a lack of solid scientific evidence for the effectiveness of pramiracetam for any of these purposes, especially in healthy humans.

Many people reported using pramiracetam for studying, both when taking in information and when recalling it during exams. But what does the science say about pramiracetam's effects on memory?

Can pramiracetam improve your memory?

Pramiracetam was found to "... partially reduce the amnesic effects induced by scopolamine both in young and old subjects." [1] in a study in which 12 participants received the "smart drug".

In one study in patients with Alzheimer's disease, pramiracetam was found ineffective for the restoration of cognitive performance [2].

In healthy elderly people with objective and subjective memory loss, pramiracetam improved memory performance more than memory training or placebo [3].

In another study [4], 400mg pramiracetam sulphate three times per day was found to improve memory, especially delayed memory recall, in four men with brain injuries and lack of oxygen. These effects were seen after 1.5 years of daily use and persisted 1 month after pramiracetam use was stopped. The apparent brain-repairing abilities of pramiracetam as measured by cognitive functioning is definitely promising, but how useful these findings are for healthy people without brain injuries is another question. The transferability of these results is limited by the fact that pramiracetam has never been found to enhance performance from baseline levels, only to restore it to closer-to-baseline levels of performance.

Pramiracetam appears to impact memory functioning in some cognitively impaired people. However, there is a lack of evidence to make any valid conclusions with confidence as regards the effectiveness of pramiracetam for healthy cognitively proficient people looking to improve their memory.


The legality and side effects of Pramiracetam


Frequently asked questions about Pramiracetam


Studies conducted on the effects of Pramiracetam in healthy humans

Last updated Saturday, June 10, 2023