Chlorogenic Acid

Other names CGA

Chlorogenic Acid

Chlorogenic Acid is a polyphenol compound found naturally in coffee and other plants. Some people use it to improve their mood, focus, and memory. But is it effective? Read on to find out what the science says.


Read about the effects of Chlorogenic Acid in relation to the amount of evidence we've found

How can you get maximum cognitive benefits from chlorogenic acid?

It is likely that you'll get the best cognitive benefits from chlorogenic acid if you consume it together with caffeine, for example through coffee. Andrew Scholey, a psychopharmacology professor at Swinburne University said the following on the Nootralize podcast about how these compounds work synergistically to optimize cognitive functioning.

”What’s really interesting about how we normally ingest caffeine is that it’s ingested with vasodilators. So if you look at caffeine in tea, tea contains catechins which we know increase blood flow. If you look at caffeine in coffee, coffee contains these things called chlorogenic acids which again increase blood flow. [...] Humans tend to ingest caffeine in a form which not only have you get caffeine in there but also there are these substances which oppose the reduction in blood flow.” ~ Nootropics researcher Andrew Scholey on the Nootralize podcast.

More specifically, what are the cognitive benefits of using chlorogenic acid?

We analyzed data from 1 placebo-controlled study on the effects of Chlorogenic Acid in healthy humans and summarized the results here:

EffectEffect sizeEvidence amount
Minute positive
Relatively large
Minute positive
Relatively large
Minute positive
Relatively large


The legality and side effects of Chlorogenic Acid

How To Use

Dose, frequency and duration


Frequently asked questions about Chlorogenic Acid


Studies conducted on the effects of Chlorogenic Acid in healthy humans

Last updated Saturday, June 10, 2023