Other names Body Protection Compound, PL 14736, PL-10, Bepecin, Stable Gastric Pentadecapeptide BPC 157


BPC-157 is a peptide that may improve focus, motivation, and mood. But how science-backed are the potential benefits of this nootropic? Read on to find out.

This nootropic has no healthy human placebo-controlled studies that meet our inclusion criteria. Negative side effects can occur if used carelessly, so make sure you’re aware of the risks of BPC-157.


Read about the effects of BPC-157 in relation to the amount of evidence we've found

Can BPC-157 enhance your cognitive performance?

There have been no studies that examined the cognitive effects of BPC-157 in humans.

The only human evidence available for the potential nootropic effects of BPC-157 is anecdotal. People tend to report increased energy levels, mental clarity, and focus, but results appear highly inconsistent. Some users speculate, referencing animal studies as their source of evidence, that their brain is going through a healing process and that this is why they have temporary negative effects from BPC-157. There's a need for more research of higher quality before any of these effects can be considered backed by science. You can read user reports and reviews below in the frequently asked questions section.

Animal studies on the cognitive and behavioral effects of BPC-157

In one rat study [2], researchers restricted the supply of blood and oxygen to the hippocampus, a brain area involved in processes related to memory and learning. They then gave these rats BPC-157 or a control substance (saline). The scientists were interested in whether BPC-157 might help heal the damage done by the lack of blood and oxygen in this brain area. They measured the results with the help of three cognitive tests:

  • Morris water maze navigation task, which tests spatial learning abilities
  • Inclined beam walk test, which tests locomotor capabilities
  • Lateral push test, which tests motor coordination

In the control group, the behavioral performance was impaired in all tasks. In the rats that received BPC-157, the behavioral capabilities were preserved. This might get you excited to click that green buy button to shop for some BPC-157. But not so fast. Conclusions that are valid and practically useful for humans who might want to use BPC-157 are hard to make for several reasons that you should be aware of:

  • It was an animal study. Animals are in many ways different than humans in how they respond to substances
  • The rats had their blood and oxygen supply to the hippocampus heavily reduced/removed. It is very unlikely that this will happen to you
  • Cognitive performance was preserved, not enhanced. There were no performance improvements compared to baseline in the rats that received BPC-157, just no impairment
  • This is only one study, it should be replicated by other research teams

Several other studies have looked at the effects of BPC-157 in animals with brain injuries or chemically induced cognitive dysfunction [3][4][5][6], generally with positive outcomes showing protective effects from BPC-157. Ultimately, these findings are promising and can be useful for researchers, but not very practically relevant to healthy people who are looking to enhance their cognitive performance.


The legality and side effects of BPC-157


Frequently asked questions about BPC-157


Studies conducted on the effects of BPC-157 in healthy humans

Last updated Saturday, June 10, 2023